PanelPlex-Consensus - PCR检测设计软件
PanelPlex-Consensus针对病毒、细菌、真菌和寄生虫的共识小组设计。提供自动化的多重PCR设计,具有覆盖率、灵敏度和特异性。
PanelPlex-Consensus已经过严格验证,可用于检测数以千计的病毒、细菌和人类目标。
它可用于以下应用:细菌、病毒的传染变体、人类基因组目标和mRNA分析。它还为单个面板提供共识设计。
PanelPlex-Consensus通过以下问题解决了这些问题:
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PanelPlex-Consensus节省了几个月(平均>6个月)的迭代实验试错优化
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通过扩展您的多重PCR分析设计流程来增加您的业务—进行更多的分析、更快的上市时间和更高的效率
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产生诊断质量设计
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经过严格验证,可检测超过1000种病毒、细菌和人类目标,并提供实验室验证结果
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DNA或RNA靶标的多种变体的自动化共识设计
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围绕各种潜在的假象进行设计,例如:由目标二级结构引起的假阴性、不需要的引物-引物相互作用、错误的引物-扩增子相互作用、背景基因组的错误扩增子,以及由于序列变异导致的低覆盖率
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PanelPlex-Consensus使用ThermoBLAST“播放列表”来扫描导致假阳性测试的脱靶杂交
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海量数据能力—PanelPlex-Consensus可以处理大型播放列表,例如人类基因组,人类RefSeq,人类微生物组、细菌多样性面板、土壤微生物或全部已知病毒
PanelPlex-Consensus通过使用包容性和排他性面板进行诊断质量分析,定期为组织节省6个月以上的工作时间。您可以自动化设计流程,缩短诊断产品的上市时间,从而节省大量的研发时间和资金。
【英文介绍】
Consensus Panel Design for viruses, bacteria, fungi, and parasited.
Providing completely automated design of multiplex PCR with unprecedented coverage, sensitivity and specificity.
PanelPlex-Consensus has been rigorously validated for the detection of thousands of viruses, bacteria and human targets.
It is useful for applications such as: infectious disease variants for bacteuia, viruses, human genomic targets, and mRNA profiling. It also provides consensus design for single panels.
PanelPlex-Consensus solves these problems by addressing the following:
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PanelPlex-Consensus saves several months (>6 months on average) of iterative experimental
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trial-and-error optimization
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Increase your business by scaling your multiplex PCR assay design process – make more assays, faster time to market, and with higher efficacy
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Produces diagnostic quality designs
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Rigorously validated for the detection of over 1000 viruses, bacteria and human targets with wet-lab validated results
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Automated consensus design of multiple variants of DNA or RNA targets
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Designs around a wide variety of potential artifacts such as: false negatives caused by target secondary structure, undesired primer-primer interactions, false primer-amplicon interactions, false amplicons to background genomes, and low coverage due to sequence variations
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PanelPlex- Consensus uses ThermoBLAST“playlists”to scan for off-target hybridizations that cause false-positive tests
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Massive data capability — PanelPlex-Consensus can handle large playlists such as human genome, human RefSeq, human microbiome, bacterial diversity panel, soil microbes, or all known viruses
PanelPlex-Consensus regularly saves organizations 6+ months in work by using inclusivity and exclusivity panels for diagnostic quality assays. You can automate the design process with faster tome to market for diagnostics, saving considerable R&D time and money.
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